A Child Presented with Clitoromegaly in Context with Neurofibromatosis Type 1

نویسندگان

چکیده

Neurofibromatosis type 1, also called Von Recklinghausen Disease is a genetic disorder characterized by the development of multiple benign tumors affecting skin and nervous system. It disease with prevalence one case in 3000 births. The cause VRD mutation [1-4]. In half all cases NF1, faulty gene passed from parent to their child. Clitoromegaly presenting childhood can be congenital or acquired. Nonhormonal causes like epidermoid cysts, tumor syndromes have been reported [5]. Clitoris enlargement frequently seen malformation, but acquired clitoral rarely detected. While most are result neurofibromin gene, there due spontaneous mutations [4]. pathological alterations behind it begin embryonic period, prior differentiation neural crest. We report 6.5 year - old female admitted for clitoromegaly an apparent deformity genital organs. girl has diagnosed context NF1 Disease. This patient was successfully treated clitoroplasty. biopsied tissue sent pathology revealed plexiform neurofibroma.

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ژورنال

عنوان ژورنال: Austin journal of clinical case reports

سال: 2021

ISSN: ['2381-912X']

DOI: https://doi.org/10.26420/austinjclincaserep.2021.1191